Specific IgE testing in allergy assessment detects which antibody class?

Specific IgE testing in allergy assessment detects which antibody class?

• A. IgG
• B. IgM
• C. IgE
• D. IgA

Answer: (C)

Allergic reactions driven by immediate-type responses rely on IgE antibodies that are specific to the allergen. Specific IgE testing looks for those allergen-specific IgE antibodies in the blood, confirming sensitization to particular allergens and supporting the diagnosis of an IgE-mediated allergy. The other antibody classes—IgG, IgM, and IgA—serve different roles in immunity and are not used to diagnose this type of allergy, since their presence does not reliably indicate allergic sensitization or clinical reactivity.

Allergic reactions driven by immediate-type responses rely on IgE antibodies that are specific to the allergen. Specific IgE testing looks for those allergen-specific IgE antibodies in the blood, confirming sensitization to particular allergens and supporting the diagnosis of an IgE-mediated allergy. The other antibody classes—IgG, IgM, and IgA—serve different roles in immunity and are not used to diagnose this type of allergy, since their presence does not reliably indicate allergic sensitization or clinical reactivity.